Very-long-chain fatty acid biosynthesis is controlled through the expression and specificity of the condensing enzyme

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Biosynthesis and Pollen Fertility, Encodes a Very-Long-Chain Fatty Acid Condensing Enzyme

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CUT1, an Arabidopsis gene required for cuticular wax biosynthesis and pollen fertility, encodes a very-long-chain fatty acid condensing enzyme.

Land plants secrete a layer of wax onto their aerial surfaces that is essential for survival in a terrestrial environment. This wax is composed of long-chain, aliphatic hydrocarbons derived from very-long-chain fatty acids (VLCFAs). Using the Arabidopsis expressed sequence tag database, we have identified a gene, designated CUT1, that encodes a VLCFA condensing enzyme required for cuticular wax...

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Biosynthesis of very long chain fatty acids by the sciatic nerve of the rabbit.

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The very-long-chain fatty acid synthase is inhibited by chloroacetamides.

The first elongation step to form very-long-chain fatty acids (VLCFAs) is catalyzed by the VLCFA-synthase. CoA-activated fatty acids react with malonyl-CoA to condense a C2-unit. As shown with recombinant enzyme this reaction is specifically inhibited by chloroacetamide herbicides. The inhibition is alleviated when the inhibitor (e.g. metazachlor) is incubated together with adequate concentrati...

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ژورنال

عنوان ژورنال: The Plant Journal

سال: 1997

ISSN: 0960-7412,1365-313X

DOI: 10.1046/j.1365-313x.1997.12010121.x